How to choose bone graft substitute for spine fusion?

Straight criteria from a medical equipment supplier in Cincinnati Children's, OH.

Contact Us (440) 488-0091

You're done harvesting iliac crest for every fusion in your practice. But now you're staring at a shelf of synthetic bone graft substitutes and every rep claims theirs is best. Cincinnati Children's spine surgeons need a clear set of criteria before their next case: porosity above 75%, silicate substitution, and actual fusion rate data.

You already know autograft has downsides: second surgical site, more pain, limited volume. Now you are comparing synthetic substitutes. They all look like white granules or putty, but they do not all behave the same. The differences come down to pore structure, surface chemistry, and evidence from real spine cases. Look for porosity above 75 percent, silicate substitution, and published fusion rates.

This decision takes a few hours of reading product data and clinical papers. Price alone will not give you a straight answer. Synthetic grafts usually cost less than BMP-2 and avoid autograft harvest costs. But the real cost is a failed fusion. A graft with poor porosity or no human data can look cheap and cost you a revision. Budget time to compare pore size, resorption rate, and handling for your approach.

This week, ask any rep for three documents: a porosity spec above 75 percent, proof of silicate substitution, and fusion data from a peer-reviewed clinical study. If they cannot show all three, move on. Then think about your approach. For MIS, you need a graft that flows through a syringe. For open posterior fusion, you need a moldable strip or block. Elite Surgical can walk Cincinnati Children's cases through ACTIFUSE and ALTAPORE formats in the OR. Call to set an in-service.

Once you have these criteria, the shelf stops looking impossible. You pick a graft with the right porosity, bioactivity, and data for your surgical approach. Your fusion has a better shot at solid bone growth. No more guessing between similar-looking products. You know why you chose it, and you can defend that choice to your value analysis committee.

Authorized distributor of Baxter ACTIFUSE
93% fusion across 694 patients, independent review
FDA cleared and used in US spine surgery since 2007

Other things people in Cincinnati Children’s ask

autograft vs synthetic bone graft substitute

Modern synthetic bone graft substitutes like ACTIFUSE and ALTAPORE show fusion rates comparable to autograft without donor site morbidity. Synthetics eliminate harvest time and reduce patient pain. Consider synthetic for single-level fusions, combine with autograft for complex cases.

bone graft substitute not integrating

Poor integration often comes from low porosity or inadequate bioactivity in the graft material. Switch to a silicate-substituted calcium phosphate with 80%+ porosity like ACTIFUSE or ALTAPORE. The enhanced porosity allows better bone ingrowth and vascularization.

consistent bone graft substitute results

Consistent results need consistent material quality and technique. Use bone graft substitutes with proven fusion rates like ALTAPORE's 86.3% rate. Ensure proper hydration, avoid overpacking, and maintain sterile handling. Elite Surgical provides technique guides for optimal results.

bone graft substitute syringe clogging

Clogging usually means the particle size is wrong for the delivery system or the material is too thick. ACTIFUSE FLOW is specifically designed for syringe delivery with consistent particle size. ACTIFUSE MIS offers minimally invasive delivery without clogging issues.

when to use bone graft substitute vs allograft

Use synthetic bone graft substitutes like ACTIFUSE when you want consistent quality without disease transmission risk. Allograft works for structural support in large defects. Synthetics are better for biological fusion enhancement in routine cases.

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Contact Us (440) 488-0091

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